Hyperbaric Oxygenation (ohp) in Massive Pulmonary Embolism.

cardiovascular surgery, pulmonary embolism remains the most serious postoperative complication. All efforts should be directed at eliminating the factors that contribute to its incidence. Recently, there has been a revival of interest in its treatment after Cooley and BealI1 reported the first successful pulmonary embolectomy using cardiopulmonary bypass in 1961. Around the same time hyperbaric oxygenation (OHP) was found beneficial in anoxic states, such as carbon monoxide poisoning, peripheral vascular insufficiency and vascular collapse. Since arterial desaturation and tissue anoxia constitute the main sequelae of massive pulmonary embolism, an experimental model was designed to simulate the clinical picture and study the effects of OHP on the biochemical, electrocardiographic changes, and survival rate of such a model. In addition, embolectomy using cardiopulmonary bypass was evaluated as a definitive therapeutic measure for pulmonary embolism.